A memetic inference method for gene regulatory networks based on S-Systems

• Published in: Proceedings of the 2004 Congress on Evolutionary Computation (IEEE Cat. No.04TH8753) Vol. 1; pp. 152 - 157 Vol.1
• Main Authors: Spieth, C., Streichert, F., Speer, N., Zell, A.
• Format: Conference Proceeding
• Language: English
• Published: Piscataway NJ IEEE 2004
• Subjects: Applied sciences; Artificial intelligence; Bioinformatics; Biological system modeling; Biological systems; Computer science; control theory; systems; DNA; Exact sciences and technology; Gene expression; Mathematical model; Probes; Proteins; Semiconductor device measurement; Systems biology; Genetic algorithm; Process planning; Evolutionary algorithm; DNA chip; Observation data; Inference; Topology; Gene expression; Bioinformatics; Modeling; Optimization; Quantitative analysis

In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. As underlying mathematical model we used S-Systems, a quantitative model, which recently has found increased attention in the literature. Due to the complexity of the inference problem so...