Clinical aspects of the apparent diffusion coefficient in 3He MRI: Results in healthy volunteers and patients after lung transplantation

• Published in: Journal of magnetic resonance imaging Vol. 25; no. 6; pp. 1152 - 1158
• Main Authors: Bink, Andrea, Hanisch, Gorden, Karg, Andrea, Vogel, Annette, Katsaros, Konstantinos, Mayer, Eckhard, Gast, Klaus K., Kauczor, Hans-Ulrich
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2007
• Subjects: Administration, Inhalation; Adult; apparent diffusion coefficient; Diffusion Magnetic Resonance Imaging - methods; Female; Helium - administration & dosage; Humans; hyperpolarized 3He MRI; Image Processing, Computer-Assisted; lung emphysema; lung fibrosis; Lung Transplantation; Male; Middle Aged; Prospective Studies; Pulmonary Diffusing Capacity; Pulmonary Emphysema - physiopathology; Pulmonary Fibrosis - physiopathology

Purpose To measure the apparent diffusion coefficient (ADC) after inhalation of hyperpolarized 3He in healthy volunteers and lung transplant recipients, and demonstrate the gravity dependence of ADC values. Materials and Methods Six healthy volunteers, 10 patients after single‐lung transplantation,...