Polymeric Nano/Microparticles for Oral Delivery of Proteins and Peptides

• Published in: Handbook of Encapsulation and Controlled Release pp. 1383 - 1404
• Format: Book Chapter
• Language: English
• Published: CRC Press 2016
• Subjects: Oral Vaccine Delivery Systems; Pharmaceutical Biotechnology; Caco-2 Cells; Diabetic Rats; IU Insulin; Alkyl Cyanoacrylate; Cellulose Acetate Phthalate; BSA Microsphere; Trimethyl Chitosan Chloride; Oral Peptide Delivery; Peyer’s Patches; TMC; Relative Pharmacological Bioavailability; Intestinal Epithelium; Mucoadhesive Polymers; Nonbiodegradable Synthetic Polymers; Hypoglycemic Effect; Oral Delivery System; Polymeric Nano; Tight Junctions; Tight Junction Permeability; Ethyl Cellulose; Delivery System; Oral Protein Delivery

Recent advancement in the field of pharmaceutical biotechnology and introduction of recombinant DNA technology have led to the production of a number of therapeutic peptides and proteins for the treatment of several life-threatening diseases (Table 57.1). A number of peptide-based therapeutics such...