A Novel Immunostimulator, N2-[α-O-Benzyl-N-(acetylmuramyl)-l-alanyl-d- isoglutaminyl]-N6-trans-(m-nitrocinnamoyl)-l-lysine, and Its Adjuvancy on the Hepatitis B Surface Antigen

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 48; no. 16; pp. 5112 - 5122
Main Authors YANG, Hong-Zhen, XU, Song, LIAO, Xue-Yan, ZHANG, Suo-De, LIANG, Zheng-Lun, LIU, Bai-He, BAI, Jin-Ye, JIANG, Chao, DING, Jian, CHENG, Gui-Fang, LIU, Gang
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 11.08.2005
Subjects
Applied microbiology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Immunomodulators
Medical sciences
Microbiology
Pharmacology. Drug treatments
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Peptides
Rat
Leukocyte
Toxicity
Tripeptide
Orthohepadnavirus
Transgenic animal
Rabbit
Cytotoxicity
Harmlessness
Interleukin 2
Hepadnaviridae
T-Lymphocyte
P815-Mastocytoma
Hepatitis B virus
Chemical synthesis
Tumor cell
Hepatitis B surface antigen
Immune response
Rodentia
Cytokine
Interleukin 12
Vaccine
Lagomorpha
In vitro
Virus
Immunomodulator
In vivo
Vertebrata
Immunostimulant agent
Mammalia
Cell line
Immunological adjuvant
Animal
Peptide synthesis
Solid phase
Gamma interferon
Macrophage
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Bibliography:istex:EB48D7F4072519B4896C76CBD63697622412B133
ark:/67375/TPS-3H6DH84M-9
ISSN:0022-2623
1520-4804
DOI:10.1021/jm0493313