Prediction of Impairment Biomarkers in Smoker Based on Machine Learning
Smoking is one of the major health issues globally, causing up to 7 million deaths each year. This paper aimed to predict impairment biomarkers in smoker based on machine learning. Firstly, we selected data set GSE37768 from the GEO database. And then, we standardized and removed batch effects from...
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Published in | 2023 3rd International Symposium on Computer Technology and Information Science (ISCTIS) pp. 460 - 464 |
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Main Authors | , , , , , , , , |
Format | Conference Proceeding |
Language | English |
Published |
IEEE
07.07.2023
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Online Access | Get full text |
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Abstract | Smoking is one of the major health issues globally, causing up to 7 million deaths each year. This paper aimed to predict impairment biomarkers in smoker based on machine learning. Firstly, we selected data set GSE37768 from the GEO database. And then, we standardized and removed batch effects from the data set. Thirdly, we select some genes through LogFC and significance tests. Lastly, the combination of 5 machine learning methods(support vector machine, random forest, decision tree, logistic regression, naive Bayes) and recursive feature elimination-cross validation was used to prediction impairment biomarkers. We found that identified biomarkers were PLSCR4, CDH3, RUNX1T1, and GUCY1A2. |
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AbstractList | Smoking is one of the major health issues globally, causing up to 7 million deaths each year. This paper aimed to predict impairment biomarkers in smoker based on machine learning. Firstly, we selected data set GSE37768 from the GEO database. And then, we standardized and removed batch effects from the data set. Thirdly, we select some genes through LogFC and significance tests. Lastly, the combination of 5 machine learning methods(support vector machine, random forest, decision tree, logistic regression, naive Bayes) and recursive feature elimination-cross validation was used to prediction impairment biomarkers. We found that identified biomarkers were PLSCR4, CDH3, RUNX1T1, and GUCY1A2. |
Author | Chen, Cai Yang, Haotian Peng, Fulai Sun, Tiefeng Lv, Danyang Wang, Xingwei Zhang, Xikun Zhang, Ningling Zhang, Yunjie |
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Snippet | Smoking is one of the major health issues globally, causing up to 7 million deaths each year. This paper aimed to predict impairment biomarkers in smoker based... |
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SubjectTerms | Biomarkers Dentistry Information science Logistic regression Lung cancer lung injury machine learning Naive Bayes methods recursive feature elimination smoking Support vector machines |
Title | Prediction of Impairment Biomarkers in Smoker Based on Machine Learning |
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