Near-infrared enzyme-activated fluorescent phospholipids for molecular imaging

• Main Author: Mawn, Theresa M
• Format: Dissertation
• Language: English
• Published: ProQuest Dissertations & Theses 01.01.2009
• Subjects: Biomedical engineering; Medical imaging; Pharmacology

With the aim of being able to detect disregulated choline lipid metabolism in cancer and elucidate the pathways involved in the malignant transformation, our group is designing and synthesizing a series of phospholipase-specific NIR molecular beacons. The focus of my dissertation has been to charact...