In Vitro and In Vivo Characterization of the Pseudomonas aeruginosa Cyclic AMP (cAMP) Phosphodiesterase CpdA, Required for cAMP Homeostasis and Virulence Factor Regulation

• Published in: Journal of Bacteriology Vol. 192; no. 11; pp. 2779 - 2790
• Main Authors: FUCHS, Erin L, BRUTINEL, Evan D, KLEM, Erich R, FEHR, Anthony R, YAHR, Timothy L, WOLFGANG, Matthew C
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.06.2010; American Society for Microbiology (ASM)
• Subjects: 3',5'-Cyclic-AMP Phosphodiesterases - chemistry; 3',5'-Cyclic-AMP Phosphodiesterases - genetics; 3',5'-Cyclic-AMP Phosphodiesterases - metabolism; ADP Ribose Transferases - genetics; ADP Ribose Transferases - metabolism; Amino Acid Sequence; Bacteria; Bacterial Proteins - chemistry; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Bacterial Toxins - genetics; Bacterial Toxins - metabolism; Bacteriology; Biochemistry; Biological and medical sciences; Blotting, Western; Chromatography, Gel; Cyclic AMP - metabolism; Cyclic AMP Receptor Protein - genetics; Cyclic AMP Receptor Protein - metabolism; DNA Footprinting; Electrophoretic Mobility Shift Assay; Eukaryotes; Exotoxins - genetics; Exotoxins - metabolism; Fundamental and applied biological sciences. Psychology; Gene expression; Gene Expression Regulation, Bacterial - genetics; Gene Expression Regulation, Bacterial - physiology; Homeostasis; Iron - metabolism; Microbiology; Miscellaneous; Molecular Sequence Data; Peptide Hydrolases - genetics; Peptide Hydrolases - metabolism; Prokaryotes; Pseudomonas aeruginosa; Pseudomonas aeruginosa - enzymology; Pseudomonas aeruginosa - genetics; Pseudomonas aeruginosa - metabolism; Pseudomonas aeruginosa Exotoxin A; Sequence Homology, Amino Acid; Signal Transduction; Virulence Factors - genetics; Virulence Factors - metabolism; Pseudomonadales; Virulence; Cyclic AMP; Homeostasis; Bacteria; Pseudomonadaceae; Pseudomonas aeruginosa; In vitro

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