Skeletal muscle microvascular flow in progressive peripheral artery disease: assessment with continuous arterial spin-labeling perfusion magnetic resonance imaging

• Published in: Journal of the American College of Cardiology Vol. 53; no. 25; pp. 2372 - 2377
• Main Authors: Wu, Wen-Chau, Mohler, 3rd, Emile, Ratcliffe, Sarah J, Wehrli, Felix W, Detre, John A, Floyd, Thomas F
• Format: Journal Article
• Language: English
• Published: United States Elsevier Limited 23.06.2009
• Subjects: Adult; Aged; Aged, 80 and over; Ankle; Arteries; Cardiology; Case-Control Studies; Data processing; Female; Humans; Leg - blood supply; Magnetic Resonance Angiography; Male; Microcirculation; Middle Aged; Muscle, Skeletal - blood supply; Muscular system; Musculoskeletal system; NMR; Nuclear magnetic resonance; Peripheral Vascular Diseases - diagnosis; Peripheral Vascular Diseases - physiopathology; Weightlifting

We present the novel application of continuous arterial spin-labeling (CASL) magnetic resonance imaging (MRI) for the measurement of calf muscle perfusion in subjects with progressive peripheral arterial disease (PAD). Peripheral arterial disease is largely considered to be a disease of conduit vess...