Excipients and additives: hidden hazards in drug products and in product substitution

• Published in: Canadian Medical Association journal Vol. 131; no. 12; pp. 1449 - 1452
• Main Authors: Napke, E, Stevens, D. G
• Format: Journal Article
• Language: English
• Published: Canada Can Med Assoc 15.12.1984
• Subjects: Benzyl Alcohols - adverse effects; Child; Coloring Agents - adverse effects; Drug Compounding; Drug Hypersensitivity; Excipients - adverse effects; Flavoring Agents - adverse effects; Humans; Pharmaceutic Aids - adverse effects; Polyethylene Glycols - adverse effects; Propylene Glycols - adverse effects; Sulfites - adverse effects

The excipients and additives in drug formulations have been described as inert because they do not have an active role in the prevention or treatment of particular ailments. This has led to the misconception among physicians, pharmacists, drug manufacturers and the public that excipients are harmles...