Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system - CHEN, Zhe-Sheng; LEE, Kun; WALTHER, Susan; RAFTOGIANIS, Rebecca Blanchard; KUWANO, Michihiko; HAO ZENG; KRUH, Gary D (Cancer research (Chicago, Ill.), 2002)
Keywords: Animals; Antimetabolites, Antineoplastic - pharmacokinetics; Antineoplastic agents; Baculoviridae - genetics; Biological and medical sciences; Carrier Proteins - metabolism; Cell Line; Chemotherapy; Folate Receptors, GPI-Anchored; Folic Acid - pharmacokinetics; Insecta - cytology; Insecta - metabolism; Insecta - virology; Liposomes; LLC-PK1 Cells - metabolism; Medical sciences; Methotrexate - analogs & derivatives; Methotrexate - pharmacokinetics; Multidrug Resistance-Associated Proteins - genetics; Multidrug Resistance-Associated Proteins - metabolism; Osmosis; Pharmacology. Drug treatments; Polyglutamic Acid - analogs & derivatives; Polyglutamic Acid - pharmacokinetics; Receptors, Cell Surface; Swine; Transfection; Antineoplastic agent; Human; Gene product; P Glycoprotein; Outward current; In vitro; Folate; Resistance; Membrane transport; Multiple resistance; Established cell line; Mechanism of action; Methotrexate; ABC transporter