Angiogenesis of uterine cervical carcinoma : Characterization by pharmacokinetic magnetic resonance parameters and histological microvessel density with correlation to lymphatic involvement

• Published in: Cancer research (Chicago, Ill.) Vol. 57; no. 21; pp. 4777 - 4786
• Main Authors: HAWIGHORST, H, KNAPSTEIN, P. G, ESSIG, M, VAUPEL, P, VAN KAICK, G, WEIKEL, W, KNOPP, M. V, ZUNA, I, KNOF, A, BRIX, G, SCHAEFFER, U, WILKENS, C, SCHOENBERG, S. O
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA American Association for Cancer Research 01.11.1997
• Subjects: Adenocarcinoma - blood supply; Adenocarcinoma - pathology; Adult; Aged; Biological and medical sciences; Capillary Permeability; Carcinoma, Squamous Cell - blood supply; Carcinoma, Squamous Cell - pathology; Female; Female genital diseases; Gynecology. Andrology. Obstetrics; Humans; Lymphatic System - pathology; Magnetic Resonance Imaging - methods; Medical sciences; Microcirculation; Middle Aged; Neovascularization, Pathologic - pathology; Observer Variation; Tumors; Uterine Cervical Neoplasms - blood supply; Uterine Cervical Neoplasms - pathology; Human; Carcinoma; Prognosis; Gadolinium compound; Histology; Malignant tumor; Uterine cervix; Potential; Nuclear magnetic resonance imaging; Female genital diseases; Angiogenesis; Microcirculation; Tumor progression; Medical imagery; Metastatic; Diagnosis; Pharmacokinetics; Uterine cervix diseases; Contrast media

Dynamic studies of Gd-based contrast agents in magnetic resonance imaging (MRI) are increasingly being used for tumor characterization as well as therapy response monitoring. Because detailed knowledge regarding the pathophysiological properties, which in turn are responsible for differences in cont...