Immunodetection of connexins and cadherins in corneal fibroblasts and myofibroblasts [published erratum appears in Invest Ophthalmol Vis Sci 1996 Nov;37(12):2366]

• Published in: Investigative ophthalmology & visual science Vol. 37; no. 9; pp. 1740 - 1748
• Main Authors: Petridou, S, Masur, SK
• Format: Journal Article
• Language: English
• Published: Rockville, MD ARVO 01.08.1996; Association for Research in Vision and Ophtalmology
• Subjects: alpha Catenin; Amino Acid Sequence; Animals; Antibodies; beta Catenin; Biological and medical sciences; Blotting, Western; Cadherins - analysis; Cadherins - immunology; Cells, Cultured; Connexin 43 - analysis; Connexins - analysis; Connexins - immunology; Cornea - cytology; Cytoskeletal Proteins - analysis; Cytoskeletal Proteins - chemistry; Cytoskeletal Proteins - immunology; Desmoplakins; Eye and associated structures. Visual pathways and centers. Vision; Fibroblasts - cytology; Fluorescent Antibody Technique; Fundamental and applied biological sciences. Psychology; Molecular Sequence Data; Peptide Fragments - chemistry; Peptide Fragments - immunology; Rabbits; Trans-Activators; Vertebrates: nervous system and sense organs; Cell culture; Cornea; Myofibroblast; Rabbit; Lagomorpha; Cadherin; Eye; Visual system; Connexin; Vertebrata; Mammalia; Microscopy; Animal; Immunoblotting assay; Immunofluorescence; Fibroblast

In normal cornea, stromal fibroblasts (keratocytes) interact with one another by gap junctions. After corneal wounding, the remaining corneal stroma cells are phenotypically fibroblasts and myofibroblasts. For insight into the respective roles of fibroblasts and myofibroblasts in wound healing, the...