Are metalloproteins and acute phase reactants associated with cardiovascular disease in end-stage renal failure?

• Published in: Annals of clinical and laboratory science Vol. 30; no. 3; pp. 295 - 304
• Main Authors: HEALY, Helen, REITH, David, MORGAN, Colleen, CLAGUE, Alan, WESTHUYZEN, Justin
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Institute for Clinical Science 01.07.2000
• Subjects: Acute-Phase Proteins - analysis; Adult; Aged; Analysis of Variance; Biological and medical sciences; Biomarkers - blood; Cardiovascular Diseases - blood; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - etiology; Cross-Sectional Studies; Diabetes Mellitus - epidemiology; Diabetic Nephropathies - epidemiology; Female; Homocysteine - blood; Humans; Kidney Failure, Chronic - blood; Kidney Failure, Chronic - complications; Kidney Failure, Chronic - therapy; Male; Medical sciences; Metalloproteins - blood; Middle Aged; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Prevalence; Regression Analysis; Renal Dialysis; Renal failure; Risk Factors; Kidney disease; Human; Transferrin; Urinary system disease; Prognosis; Ferritin; Cardiovascular disease; Terminal stage; Iron; Metalloproteins; Binding capacity; Risk factor; Renal failure; Copper; C reactive protein

End-stage renal failure (ESRF) is associated with a higher risk of cardiovascular disease (CVD) than predicted by the major risk factors. We investigate the hypothesis that metalloproteins such as transferrin and ceruloplasmin and the inflammatory response are associated with CVD risk in this popula...