O2-sensitive K+ channels in neuroepithelial body-derived small cell carcinoma cells of the human lung

• Published in: American journal of physiology. Lung cellular and molecular physiology Vol. 275; no. 4; p. 709
• Main Authors: O'Kelly, I, Peers, C, Kemp, P. J
• Format: Journal Article
• Language: English
• Published: United States 01.10.1998
• Subjects: Cadmium - pharmacology; Carcinoma, Small Cell - physiopathology; Cell Hypoxia - physiology; Epithelial Cells - physiology; Humans; Ion Channel Gating; Lung Neoplasms - physiopathology; Membrane Potentials - drug effects; Oxygen - metabolism; Potassium Channels - drug effects; Potassium Channels - physiology; Tetraethylammonium - pharmacology; Tetrodotoxin - pharmacology; Tumor Cells, Cultured

1  Department of Physiology and 2  Institute for Cardiovascular Research, University of Leeds, Leeds LS2 9JT, United Kingdom Neuroepithelial bodies act as airway O 2 sensors, but studies of their activity at the cellular level have been severely limited because they are present at such a low density...