Labeling of Red Blood Cells with Tc-99m after Oral Administration of SnCl2: Concise Communication

• Published in: The Journal of nuclear medicine (1978) Vol. 20; no. 8; pp. 877 - 881
• Main Authors: Patel, M. C, Parab, P. B, Samuel, A. M, Ganatra, R. D
• Format: Journal Article
• Language: English
• Published: United States Soc Nuclear Med 01.08.1979
• Subjects: Administration, Oral; Animals; Erythrocytes; Humans; Isotope Labeling - methods; Pericardial Effusion - diagnostic imaging; Radionuclide Imaging; Rats; Technetium - metabolism; Tin - administration & dosage; Tin - metabolism; Tin Compounds; Tissue Distribution

In vivo labeling of red blood cells with Tc-99m was possible after prior oral administration of SnCl2, both in rats and human volunteers. Absorption of oral SnCl2 was low but sufficient for more than 95% labeling efficiency. Prior i.v. administration of stannous chloride is known to induce in vivo l...