Determinants of Progression of Coronary Artery Calcification in Type 2 Diabetes : Role of Glycemic Control and Inflammatory/Vascular Calcification Markers

• Published in: Journal of the American College of Cardiology Vol. 50; no. 23; pp. 2218 - 2225
• Main Authors: VIJAY ANAND, Dhakshinamurthy, LIM, Eric, DARKO, Daniel, BASSETT, Paul, HOPKINS, David, LIPKIN, David, CORDER, Roger, LAHIRI, Avijit
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Science 04.12.2007; Elsevier Limited
• Subjects: Adult; Aged; Biological and medical sciences; Biomarkers - blood; Body mass index; C-Reactive Protein - metabolism; Calcinosis - blood; Calcinosis - diagnostic imaging; Calcinosis - etiology; Cardiology; Cardiology. Vascular system; Cardiovascular disease; Cholesterol; Cohort Studies; Coronary Artery Disease - blood; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - etiology; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - diagnostic imaging; Disease Progression; Drug therapy; Female; Glycated Hemoglobin A - metabolism; Heart attacks; Humans; Interleukin-6 - blood; Male; Medical sciences; Middle Aged; Osteoprotegerin - blood; Risk Factors; Severity of Illness Index; Tomography, X-Ray Computed; United States > US; California; Endocrinopathy; Type 2 diabetes; Prognosis; Determinant; Coronary artery; Biological marker; Metabolic diseases; Inflammation; Blood vessel; Calcification; Evolution; Circulatory system; Cardiology; Glycemia

This study prospectively evaluated the relationship between cardiovascular risk factors, selected biomarkers (high-sensitivity C-reactive protein [hs-CRP], interleukin [IL]-6, and osteoprotegerin [OPG]), and the progression of coronary artery calcification (CAC) in type 2 diabetic subjects. Coronary...