6-L-18F-Fluorodihydroxyphenylalanine PET in Neuroendocrine Tumors: Basic Aspects and Emerging Clinical Applications

• Published in: The Journal of nuclear medicine (1978) Vol. 49; no. 4; pp. 573 - 586
• Main Authors: Jager, Pieter L, Chirakal, Raman, Marriott, Christopher J, Brouwers, Adrienne H, Koopmans, Klaas Pieter, Gulenchyn, Karen Y
• Format: Journal Article
• Language: English
• Published: United States Soc Nuclear Med 01.04.2008
• Subjects: Adenoma, Islet Cell - diagnostic imaging; Dihydroxyphenylalanine - analogs & derivatives; Humans; Hyperinsulinism - diagnostic imaging; Neuroendocrine Tumors - diagnostic imaging; Pancreatic Neoplasms - diagnostic imaging; Pheochromocytoma - diagnostic imaging; Positron-Emission Tomography; Thyroid Neoplasms - diagnostic imaging

In recent years, 6-l-18F-fluorodihydroxyphenylalanine (18F-DOPA) PET has emerged as a new diagnostic tool for the imaging of neuroendocrine tumors. This application is based on the unique property of neuroendocrine tumors to produce and secrete various substances, a process that requires the uptake...