The multivalent G-quadruplex (G4)-ligands MultiTASQs allow for versatile click chemistry-based investigations

• Published in: bioRxiv
• Main Authors: Francesco Rota Sperti, Mitteaux, Jeremie, Zell, Joanna, Pipier, Angelique, Valverde, Ibai E, Monchaud, David
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 31.10.2022
• Subjects: Chemistry; Ligands

Chemical biology hinges on multivalent molecular tools that uniquely allow for interrogating and/or manipulating cellular circuitries from the inside. The success of many of these approaches relies on molecular tools that make it possible to visualize biological targets in cells and then isolate the...