Combination of white matter hyperintensities and A[beta] burden is related to cognitive composites domain scores in subjective cognitive decline: the FACEHBI cohort

• Published in: Alzheimer's research & therapy Vol. 13; no. 1
• Main Authors: Ortega, G, Espinosa, A, Alegret, M, Monté-Rubio, GC, Sotolongo-Grau, O, Sanabria, A, Tartari, JP, Rodríguez-Gómez, O, Marquié, M, Vivas, A, Gómez-Chiari, M, Alarcón-Martín, E, Pérez-Cordón, A, Roberto, N, Hernández, I, Rosende-Roca, M, Vargas, L, Mauleón, A, Abdelnour, C, Esteban De Antonio, E, López-Cuevas, R, Alonso-Lana, S, Moreno-Grau, S, de Rojas, I, Orellana, A, Montrreal, L, Tárraga, L, Ruiz, A, Boada, M, Valero, S, Aguilera, N, Berthier, M, Buendia, M, Bullich, S, Campos, F, Caéabate, P, Caéada, L, Cuevas, C, Diego, S, Gailhajenet, A, García, P, Giménez, J, Gismondi, R, Guitart, M, Ibarria, M, Lafuente, A, Lomeéa, F, Masip, E, Martín, E, Martínez, J, Moreno, M, Niéerola, A, Nogales, A. B, Núéez, L, Páez, A, Pancho, A, Pelejà, E, Pérez-Grijalba, V, Perissinotti, A, Pesini, P, Preckler, S, Roé-Vellvé, N, Romero, J, Ramis, M. I, Sarasa, M, Tejero, M. A, Torres, M
• Format: Journal Article
• Language: English
• Published: BioMed Central Ltd 17.08.2021
• Subjects: Amyloid beta-protein; Apolipoproteins; Cognition disorders; Diagnosis; Health aspects; Risk factors; Spain

Background To explore whether the combination of white matter hyperintensities (WMHs) and amyloid-beta (A[beta]) deposition is associated with worse cognitive performance on cognitive composites (CCs) domain scores in individuals with subjective cognitive decline (SCD). Methods Two hundred participa...