Significance of the Balance between Regulatory T Cells during Hepatitis B Virus Related Liver Fibrosis

• Published in: PloS one Vol. 7; no. 6; p. e39307
• Main Authors: Li, Jing, Qiu, Shuang-Jian, She, Wei-Min, Wang, Fu-Ping, Gao, Hong, Li, Lei, Tu, Chuan-Tao, Wang, Ji-Yao, Shen, Xi-Zhong, Jiang, Wei
• Format: Journal Article
• Language: English
• Published: Public Library of Science 20.06.2012
• Subjects: Analysis; Development and progression; Fibrosis; Hepatitis B; Inflammation; Interleukins; Liver

Background Hepatitis B virus-related liver fibrosis (HBV-LF) always progresses from inflammation to fibrosis. However, the relationship between these two pathological conditions is not fully understood. Here, it is postulated that the balance between regulatory T (Treg) cells and T helper 17 (Th17)...