Early and Mid-Term Disposition of [alpha]-PVP and its unknown Metabolites in Urine and Oral Fluid Through a Multi-Analytical Hyphenated Approach Following a Single Non-Controlled Administration to Healthy Volunteers

• Published in: The AAPS journal Vol. 27; no. 1
• Main Authors: Di Trana, Annagiulia, La Maida, Nunzia, de la Rosa, Georgina, Di Giorgi, Alessandro, Graziano, Silvia, Aldhaehri, Khaled, Papaseit, Esther
• Format: Journal Article
• Language: English
• Published: Springer 01.02.2025
• Subjects: Data mining; Metabolites

Nowadays, synthetic cathinones (SCs) is the second more representative subclass of New Psychoactive Substances, accounting for 104 analogues in the illegal market. Since its first report in 2011, [alpha]-pyrrolidinovalerophenone ([alpha]-PVP) gained popularity among drug users, provoking an increase...