Genomic Characterization of IMP-Producing IPseudomonas aeruginosa/I in Bulgaria Reveals the Emergence of IMP-100, a Novel Plasmid-Mediated Variant Coexisting with a Chromosomal VIM-4

• Published in: Microorganisms (Basel) Vol. 11; no. 9
• Main Authors: Stoikov, Ivan, Ivanov, Ivan N, Donchev, Deyan, Teneva, Deana, Dobreva, Elina, Hristova, Rumyana, Sabtcheva, Stefana
• Format: Journal Article
• Language: English
• Published: MDPI AG 01.09.2023
• Subjects: Beta lactamases; Drug resistance in microorganisms; Genetic aspects; Imipenem; Physiological aspects; Pseudomonas aeruginosa; Bulgaria

Multidrug-resistant (MDR) Pseudomonas aeruginosa infections represent a major public health concern and require comprehensive understanding of their genetic makeup. This study investigated the first occurrence of imipenemase (IMP)-carrying P. aeruginosa strains from Bulgaria. Whole genome sequencing...