Epithelial Cell Adhesion Molecule Expression Can Be Modulated via INFκB/I

• Published in: Biomedicines Vol. 10; no. 11
• Main Authors: Zia, Saadiya, Tehreem, Komal, Batool, Sidra, Ishfaq, Mehreen, Mirza, Shaher Bano, Khan, Shahrukh, Almashjary, Majed N, Hazzazi, Mohannad S, Qanash, Husam, Shaikh, Ahmad, Baty, Roua S, Jafri, Ibrahim, Alsubhi, Nouf H, Alrefaei, Ghadeer I, Sami, Rokayya, Shahid, Ramla
• Format: Journal Article
• Language: English
• Published: MDPI AG 01.11.2022
• Subjects: Cancer; Care and treatment; Cell adhesion; Epithelial cells; Gene expression; Genes; Genetic aspects; Medicinal plants; Medicine, Botanic; Medicine, Herbal; Observations; Telomeres; Pakistan; Saudi Arabia

The epithelial cell adhesion molecule (EpCAM) is considered an essential proliferation signature in cancer. In the current research study, qPCR induced expression of EpCAM was noted in acute lymphoblastic leukemia (ALL) cases. Costunolide, a sesquiterpene lactone found in crepe ginger and lettuce, i...