Biophysics of Nucleic Acids Celebrating the 75th Birthday of Professor Kenneth J. Breslauer

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: ab initio methods; AMBER; aptamer; ATP sensor; aurintricarboxylic acid (ATA); B-DNA; biological function and viral disease; biological structure database; Biology, life sciences; biosensor; brines; calorimetry; CD spectroscopy; charge; computational biophysics; DNA; DNA conjugate; DNA curvature; DNA deformability; DNA minicircles; DNA minor groove binder; DNA sequence context; DNA sequence-dependent structure; DNA-hairpin; DNA-protein networks; DNAzyme; drug discovery; drug-like properties; drug-target interactions; dsDNA–dsDNA interactions; electrostatic potential; enthalpic efficiency; fitting; flexibility; fluctuation theorems; folding; forcefield; fragment-based drug discovery; G-quadruplex; G-quadruplexes; group efficiency; habitability; heterocyclic diamidine; human serum albumin (HSA); hydrostatic pressure; inhibitor binding; isothermal titration calorimetry; kinetic models; kinetics; lanthanide; lead optimization; ligand; ligand–DNA complex thermodynamic; lipophilic efficiency; Mars; Mathematics and Science; metal ion; methylene-salicylic acid; minor groove binding drugs; mixed base-pair DNA sequences; molecular curvature; molecular dynamics; molecular dynamics simulation (MD); molecular recognition; n/a; NMR spectroscopy; nucleic acid conformation; nucleic acid structures; nucleic acid thermodynamics; nucleic acids; optical spectroscopy; origins of life; perchlorates; polymorphism; potassium; potential of mean force (PMF); pressure; protocells; quadruplex-duplex hybrids; Reference, Information and Interdisciplinary subjects; replication; Research and information: general; RNA; RNA-dependent RNA polymerase (RdRp); salicylic acid polymers; SARS-CoV-2; sequence edition; sequence selectivity; silver ion; single-molecule biophysics; stability; statistical mechanics; terpyridine; thermodynamic binding signatures; thermodynamics; topology; triple helix; validation standards; volume; yeast ribosomes

This Special Issue comprises 15 papers broadly outlining current trends in nucleic acid biophysics. It contains original research papers and reviews on structure, stability, and interactions of canonical and non-canonical nucleic acids. The authors describe the use of established, time-honored exper...