Antimicrobial Peptides Aka Host Defense Peptides – From Basic Research to Therapy

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: 15N- and 19F-NMR; aggregation; AMP; AMPs; anti-infective activity; antibacterial effect; antimicrobial activity; antimicrobial peptide; antimicrobial peptides; antimicrobial peptidomimetic; apolipoprotein E; body fluid; bulky non-nature amino acid; cancer; cationic antimicrobial peptides; cecropin-like; chemical barrier; Chemistry; DAMPs; drug design; ECP; Escherichia coli NBIMCC 8785; expression; extracellular traps; fluorescence and digital assays; Gram-negative bacteria; hemolysis; host defense; host defense peptide; host defense peptides; human cathelicidin; hyaluronic acid; hydrogel-based system; immunomodulation; infection; innate immunity; intein; interaction network; length dependent activity; LPS; Mathematics and Science; membrane integrity; monocytes; mucus of Cornu aspersum; murine model; neutrophils; neutrophil–monocyte interaction; NF-κB; oncolytic peptides; oral cavity; peptide fraction MW < 10 kDa; poly I:C; Reference, Information and Interdisciplinary subjects; Research and information: general; self-cleavage; SEM; skin infections; solid-state 31P; structure and orientation of peptides in membranes; toll-like receptor 3; vesicle leakage; β-sheets; β-stranded peptides

This Special Issue reprint will address the most current and innovative developments in the field of HDP research across a range of topics, such as structure and function analysis, modes of action, anti-microbial effects, cell and animal model systems, the discovery of novel host-defense peptides, a...