Genome editing of the disease susceptibility gene CsLOB1 in citrus confers resistance to citrus canker

• Published in: Plant biotechnology journal Vol. 15; no. 7; pp. 817 - 823
• Main Authors: Jia, Hongge, Zhang, Yunzeng, Orbović, Vladimir, Xu, Jin, White, Frank F., Jones, Jeffrey B., Wang, Nian
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.07.2017; John Wiley and Sons Inc
• Subjects: adverse effects; Bacteria; bacterial canker; breeding; Candidatus Liberibacter asiaticus; Canker; Cas9; Citrus - genetics; Citrus - microbiology; Citrus canker; Citrus fruits; Citrus greening; Citrus paradisi; CRISPR; crop production; Disease control; Disease resistance; Disease Resistance - genetics; Disease susceptibility; Disease Susceptibility - metabolism; Editing; Fruits; Gene Editing; Gene Expression Regulation, Plant - genetics; genes; Genetic aspects; Genetic research; Genome editing; Genomes; Genomics; Grapefruit; grapefruits; greening disease; Health aspects; high-throughput nucleotide sequencing; juvenility; Mutation; Pathogens; Plant bacterial diseases; Plant breeding; Plant diseases; Plant Diseases - genetics; Plant Diseases - microbiology; Plants (botany); Plants, Genetically Modified - genetics; Plants, Genetically Modified - microbiology; polyembryony; Polyploidy; RNA, Plant - genetics; sgRNA; Side effects; Target detection; Tree crops; trees; Xanthomonas citri; Xanthomonas citri; Cas9; sgRNA; Citrus paradisi

Citrus is a highly valued tree crop worldwide, while, at the same time, citrus production faces many biotic challenges, including bacterial canker and Huanglongbing (HLB). Breeding for disease‐resistant varieties is the most efficient and sustainable approach to control plant diseases. Traditional b...