Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

• Published in: Nature medicine Vol. 26; no. 8; pp. 1200 - 1204
• Main Authors: Long, Quan-Xin, Tang, Xiao-Jun, Shi, Qiu-Lin, Li, Qin, Deng, Hai-Jun, Yuan, Jun, Hu, Jie-Li, Xu, Wei, Zhang, Yong, Lv, Fa-Jin, Su, Kun, Zhang, Fan, Gong, Jiang, Wu, Bo, Liu, Xia-Mao, Li, Jin-Jing, Qiu, Jing-Fu, Chen, Juan, Huang, Ai-Long
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.08.2020; Nature Publishing Group
• Subjects: 692/699/255; 692/699/255/2514; Adolescent; Adult; Aged; Antibodies; Asymptomatic; Asymptomatic Infections; Betacoronavirus - immunology; Betacoronavirus - pathogenicity; Biomedical and Life Sciences; Biomedicine; Cancer Research; Carbon monoxide; Child; China - epidemiology; Coronavirus Infections - blood; Coronavirus Infections - epidemiology; Coronavirus Infections - immunology; Coronavirus Infections - virology; Coronaviruses; COVID-19; Cytokines; Cytokines - blood; Cytokines - immunology; Female; Genetic testing; Health aspects; Hospitalization; Humans; Immune response; Immune system; Immunity, Innate; Immunoglobulin G; Immunoglobulin G - blood; Immunoglobulin G - immunology; Immunology; Infectious Diseases; Inflammation; Letter; Male; Metabolic Diseases; Middle Aged; Molecular Medicine; Neurosciences; Neutralizing; Pandemics; Patients; Physiological aspects; Pneumonia, Viral - blood; Pneumonia, Viral - epidemiology; Pneumonia, Viral - immunology; Pneumonia, Viral - virology; Reduction; SARS-CoV-2; Serological surveys; Severe acute respiratory syndrome coronavirus 2; Testing; Viral diseases; Viruses; Young Adult; China

The clinical features and immune responses of asymptomatic individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been well described. We studied 37 asymptomatic individuals in the Wanzhou District who were diagnosed with RT–PCR-confirmed SARS-CoV-2 infection...