Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth

• Published in: South African medical journal Vol. 100; no. 1; pp. 58 - 64
• Main Authors: STRINGER, Elizabeth, READ, Jennifer S, HOFFMAN, Irving, VALENTINE, Megan, ABOUD, Said, GOLDENBERG, Robert L
• Format: Journal Article
• Language: English
• Published: Rondebosch Health and Medical Publishing Group 2010; Health & Medical Publishing Group
• Subjects: Adult; Africa South of the Sahara; Anti-Infective Agents - therapeutic use; Biological and medical sciences; Birth weight, Low; Care and treatment; Cohort Studies; Diagnosis; Diseases of mother, fetus and pregnancy; Erythromycin - therapeutic use; Female; General aspects; Gynecology. Andrology. Obstetrics; Human immunodeficiency virus; Human protozoal diseases; Humans; Infant, Low Birth Weight; Infant, Newborn; Infectious diseases; Medical sciences; Metronidazole - therapeutic use; Parasitic diseases; Parasitic diseases due to ciliates and flagellates; Patient outcomes; Pregnancy; Pregnancy Complications, Parasitic - drug therapy; Pregnancy Complications, Parasitic - epidemiology; Pregnancy. Fetus. Placenta; Premature birth; Premature Birth - epidemiology; Protozoal diseases; Risk factors; Treatment Outcome; Trichomonas vaginalis; Trichomonas Vaginitis - complications; Trichomonas Vaginitis - drug therapy; Trichomoniasis; Young Adult; Sub-Saharan Africa; Africa; Africa South of the Sahara; South Africa; Infection; Pregnancy; Newborn diseases; Protozoal disease; Treatment; Pregnancy disorders; Prematurity; Trichomoniasis; Low birth weight; Premature delivery; Tropical medicine; Parasitosis

To determine whether treatment of trichomoniasis increases the risk of prematurity. Sub-analysis of a randomised trial. We analysed data from HPTN trial of antenatal and intrapartum antibiotics to reduce chorioamnionitis-related perinatal HIV transmission. Pregnant women from four sites in Africa. G...