Demonstration of a hyperglycemia-driven pathogenic abnormality of copper homeostasis in diabetes and its reversibility by selective chelation : Quantitative comparisons between the biology of copper and eight other nutritionally essential elements in normal and diabetic individuals - COOPER, Garth J. S; CHAN, Yih-Kai; DISSANAYAKE, Ajith M; LEAHY, Fiona E; KEOGH, Geraldine F; FRAMPTON, Chris M; GAMBLE, Gregory D; BRUNTON, Dianne H; BAKER, John R; POPPITT, Sally D (Diabetes (New York, N.Y.), 2005)
Keywords: Adult; Aged; Animals; Biological and medical sciences; Calcium - blood; Calcium - metabolism; Causes of; Copper - blood; Copper - metabolism; Diabetes; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - metabolism; Diabetes research; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Feces - chemistry; Glucose; Glycated Hemoglobin A - metabolism; Health aspects; Heart failure; Homeostasis; Humans; Hyperglycemia; Hyperglycemia - blood; Hyperglycemia - metabolism; Infant; Medical sciences; Metabolism; Middle Aged; Nutrition; Oxidative stress; Rats; Reference Values; Regression Analysis; Regulatory approval; Trace Elements - blood; Trace Elements - metabolism; Urine; United States; Endocrinopathy; Human; Hyperglycemia; Diabetes mellitus; Homeostasis; Reversibility; Copper