Blood letting in high-ferritin type 2 diabetes: Effects on insulin sensitivity and β-cell function

• Published in: Diabetes (New York, N.Y.) Vol. 51; no. 4; pp. 1000 - 1004
• Main Authors: FERNANDEZ-REAL, José Manuel, PENARROJA, Georgina, CASTRO, Antoni, GARCIA-BRAGADO, Fernando, HERNANDEZ-AGUADO, Ildefonso, RICART, Wifredo
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.04.2002
• Subjects: Analysis of Variance; Area Under Curve; Biological and medical sciences; Blood Glucose - metabolism; Blood Pressure; C-Peptide - blood; C-Reactive Protein - metabolism; Care and treatment; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - physiopathology; Ferritins - blood; Glucagon - blood; Glycated Hemoglobin A - metabolism; Hematocrit; Humans; Insulin - blood; Insulin - metabolism; Insulin resistance; Insulin Secretion; Islets of Langerhans - metabolism; Phlebotomy; Smoking; Transferrin - metabolism; Type 2 diabetes; Spain

Iron-related insulin-resistance is improved by iron depletion or treatment with iron chelators. The aim of this study was to evaluate insulin sensitivity and insulin secretion after blood letting in patients who had high-ferritin type 2 diabetes and were randomized to blood letting (three phlebotomi...