Nuclear Magnetic Resonance Structure Elucidation of Peptide b2 Ions

• Published in: Angewandte Chemie International Edition Vol. 54; no. 5; pp. 1547 - 1550
• Main Authors: Liu, Pengyuan, Cooks, R. Graham, Chen, Hao
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 26.01.2015; WILEY‐VCH Verlag; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: Amino Acid Sequence; Atmospheric Pressure; fragments; Ions; Ions - chemistry; Mass spectrometry; Molecular Conformation; NMR; NMR spectroscopy; Nuclear magnetic resonance; Nuclear Magnetic Resonance, Biomolecular; peptides; Peptides - chemistry; Scientific imaging; Spectrometry, Mass, Electrospray Ionization; structure elucidation; mass spectrometry; peptides; fragments; structure elucidation; NMR spectroscopy

Tandem mass spectrometry (MS/MS) is powerful for chemical identification but it is still insufficient for explicit ion structure determination. A strategy is introduced to elucidate MS fragment ion structures using NMR spectroscopy for the first time. In our experiments, precursor ions are dissociat...