Efficacy of glucosamine alendronate alone & in combination with dihydroquercetin for treatment of osteoporosis in animal model

• Published in: Indian journal of medical research (New Delhi, India : 1994) Vol. 135; no. 2; pp. 221 - 227
• Main Authors: Muraleva, Natalya A, Ofitserov, Evgeniy N, Tikhonov, Vladimir P, Kolosova, Natalya G
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.02.2012; Medknow Publications & Media Pvt Ltd
• Subjects: Alendronate; Alendronate - administration & dosage; Alendronate - adverse effects; Animals; Bone Density - drug effects; Bone Density Conservation Agents - administration & dosage; Calcium - blood; Collagen Type I - blood; Drug Synergism; Drug therapy; Glucosamine; Glucosamine - administration & dosage; Glucosamine - analogs & derivatives; Health aspects; Humans; Male; Original; Osteocalcin - blood; Osteoporosis; Osteoporosis - drug therapy; Physiological aspects; Quercetin; Quercetin - administration & dosage; Quercetin - analogs & derivatives; Rats; Rats, Wistar; India

Considerable efforts are being made to develop new, more effective drugs for osteoporosis, including novel forms of bisphosphonates. The present study was carried out to compare the effect of a novel agent glucosamine alendronate (GA) alone and is combination with dihydroquercetin (DHQ) against the...