Cold-induced expression of delta-desaturase in carp by transcriptional and posttranslational mechanisms

• Published in: Science (American Association for the Advancement of Science) Vol. 271; no. 5250; pp. 815 - 818
• Main Authors: Tiku, P.E, Gracey, A.Y, Macartney, A.I, Beynon, R.J, Cossins, A.R
• Format: Journal Article
• Language: English
• Published: American Association for the Advancement of Science 09.02.1996
• Subjects: Ectothermy; Genetic transcription; Poikilotherms; Post-translational modification; Post-translational modifications; Transcription (Genetics)

Poikilothermic animals respond to chronic cold by increasing phosphoglyceride unsaturation to restore the fluidity of cold-rigidified membranes. Despite the importance of this compensatory response, the enzymes involved have not been clearly identified, and the mechanisms that control their activity...