Meta-path Based MiRNA-Disease Association Prediction

• Published in: Database Systems for Advanced Applications Vol. 11448; pp. 34 - 48
• Main Authors: Lv, Hao, Li, Jin, Zhang, Sai, Yue, Kun, Wei, Shaoyu
• Format: Book Chapter
• Language: English
• Published: Switzerland Springer International Publishing AG 2019; Springer International Publishing
• Series: Lecture Notes in Computer Science
• Subjects: Association prediction; Disease; Heterogeneous Information Network; Link prediction; Meta-paths; MiRNA

Predicting the association of miRNA with disease is an important research topic of bioinformatics. In this paper, a novel meta-path based approach MPSMDA is proposed to predict the association of miRNA-disease. MPSMDA uses experimentally validated data to build a miRNA-disease heterogeneous informat...