The value of the dental impaction pain model in drug development

• Published in: Methods in molecular biology (Clifton, N.J.) Vol. 617; p. 175
• Main Authors: Cooper, Stephen A, Desjardins, Paul J
• Format: Journal Article
• Language: English
• Published: United States 01.01.2010
• Subjects: Acetaminophen - therapeutic use; Analgesics, Non-Narcotic - therapeutic use; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use; Drug Design; Humans; Mefenamic Acid - therapeutic use; Models, Biological; Pain - drug therapy; Pain Measurement - methods; Pain Threshold; Pain, Postoperative - drug therapy; Placebos; Reproducibility of Results; Sensitivity and Specificity; Tooth, Impacted - drug therapy; Tooth, Impacted - physiopathology

The modern version of the Dental Impaction Pain Model (DIPM) was developed in the mid-1970s. Since that time, several hundred studies have been conducted by numerous investigators. Today it is arguably the most utilized of all the acute pain models. Its popularity is due to the success rate of the s...