Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model

• Published in: Journal of endourology Vol. 24; no. 3; p. 355
• Main Authors: Kaplon, Daniel M, Penniston, Kristina L, Darriet, Camille, Crenshaw, Thomas D, Nakada, Stephen Y
• Format: Journal Article
• Language: English
• Published: United States 01.03.2010
• Subjects: Acids - metabolism; Animals; Diet; Disease Models, Animal; Female; Glycolates - urine; Hydrogen-Ion Concentration - drug effects; Hydroxyproline - toxicity; Hyperoxaluria - chemically induced; Hyperoxaluria - urine; Oxalates - urine; Sus scrofa

Swine models have proven useful for many different disease processes, especially for urologic research. In this study, we sought to create a model of hyperoxaluria in the adult sow by feeding hydroxyproline (HP). The development of an adult porcine model for calcium oxalate stone disease would repre...