N-terminal pro Brain Natriuretic Peptide as predictor of outcome in scleroderma renal crisis

• Published in: Clinical and experimental rheumatology Vol. 34 Suppl 100; no. 5; p. 122
• Main Authors: Chighizola, Cecilia Beatrice, Pregnolato, Francesca, Meroni, Pier Luigi, Denton, Christopher Paul, Ong, Voon H
• Format: Journal Article
• Language: English
• Published: Italy 01.09.2016
• Subjects: Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Antihypertensive Agents - therapeutic use; Area Under Curve; Biomarkers - blood; Glomerular Filtration Rate; Humans; Hypertension - blood; Hypertension - diagnosis; Hypertension - etiology; Hypertension - therapy; Kidney - physiopathology; Likelihood Functions; Linear Models; Logistic Models; Multivariate Analysis; Natriuretic Peptide, Brain - blood; Odds Ratio; Peptide Fragments - blood; Predictive Value of Tests; Principal Component Analysis; Recovery of Function; Renal Insufficiency - blood; Renal Insufficiency - diagnosis; Renal Insufficiency - etiology; Renal Insufficiency - therapy; Renal Replacement Therapy; Retrospective Studies; Risk Assessment; Risk Factors; ROC Curve; Scleroderma, Systemic - blood; Scleroderma, Systemic - complications; Scleroderma, Systemic - diagnosis; Time Factors; Treatment Outcome
• ISSN: 0392-856X

Although in scleroderma renal crisis (SRC) outcome has improved to a great extent with the introduction of ACE inhibitors, there remains significant mortality and morbidity with frequent requirement for renal replacement therapy. Therefore, novel biomarkers to identify patients at high risk of poor...