Impact of Intraprocedural Stent Thrombosis During Percutaneous Coronary Intervention: Insights From the CHAMPION PHOENIX Trial (Clinical Trial Comparing Cangrelor to Clopidogrel Standard of Care Therapy in Subjects Who Require Percutaneous Coronary Intervention)

• Published in: Journal of the American College of Cardiology Vol. 63; no. 7; pp. 619 - 629
• Main Authors: GENEREUX, Philippe, STONE, Gregg W, TIEPU LIU, TODD, Meredith, SKERJANEC, Simona, HAMM, Christian W, MAHAFFEY, Kenneth W, WHITE, Harvey D, BHATT, Deepak L, HARRINGTON, Robert A, GIBSON, C. Michael, STEG, Ph. gabriel, BRENER, Sorin J, ANGIOLILLO, Dominick J, PRICE, Matthew J, PRATS, Jayne, LASALLE, Laura
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier 25.02.2014; Elsevier Limited
• Subjects: Adenosine; Adenosine Monophosphate - administration & dosage; Adenosine Monophosphate - analogs & derivatives; Aged; Angina pectoris; Angioplasty; Biological and medical sciences; Blood clots; Cardiology; Cardiology. Vascular system; Clinical trials; Clopidogrel; Coronary heart disease; Diseases of the cardiovascular system; Double-Blind Method; Female; Heart; Heart attacks; Humans; Implants; Intraoperative Complications - diagnosis; Intraoperative Complications - epidemiology; Intravenous administration; Ischemia; Laboratories; Male; Medical sciences; Middle Aged; Myocardial infarction; Patients; Percutaneous Coronary Intervention - methods; Percutaneous Coronary Intervention - standards; Prospective Studies; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Standard of Care - standards; Stents - adverse effects; Thrombosis; Thrombosis - diagnosis; Thrombosis - epidemiology; Ticlopidine - administration & dosage; Ticlopidine - analogs & derivatives; Treatment Outcome; North Carolina; New York; United States > US; Cangrelor; Angioplasty; Cardiovascular disease; Standard; Knowledge; Stent; Percutaneous route; Vascular disease; Antithrombotic agent; Clinical trial; Cardiology; WHO; Human; Endoprosthesis; Atherectomy; Coronary artery; Instrumentation therapy; Coronary heart disease; Thrombosis; Antiplatelet agent; Standards; Care; Clopidogrel; Circulatory system; Thienopyridine derivative; Comparative study; IPST; cangrelor; stent thrombosis; PCI
• ISSN: 0735-1097; 1558-3597; 1558-3597
• DOI: 10.1016/j.jacc.2013.10.022

This study sought to evaluate the clinical impact of intraprocedural stent thrombosis (IPST), a relatively new endpoint. In the prospective, double-blind, active-controlled CHAMPION PHOENIX (Clinical Trial Comparing Cangrelor to Clopidogrel Standard of Care Therapy in Subjects Who Require Percutaneo...