Sublingual buprenorphine versus intravenous or intramuscular morphine in acute pain: A systematic review and meta-analysis of randomized control trials

• Published in: The American journal of emergency medicine Vol. 37; no. 3; p. 381
• Main Authors: Vlok, Ruan, An, Gun Hee, Binks, Matthew, Melhuish, Thomas, White, Leigh
• Format: Journal Article
• Language: English
• Published: Philadelphia Elsevier Limited 01.03.2019
• Subjects: Abdominal surgery; Analgesia; Analgesics; Anesthesia; Bias; Buprenorphine; Cholecystectomy; Clinical trials; Collaboration; Data processing; Drug overdose; Emergency medical care; Evidence-based medicine; Hypotension; Intravenous administration; Meta-analysis; Morphine; Narcotics; Nausea; Pain; Pain perception; Pruritus; Quality; Randomization; Systematic review; Vomiting

IntroBuprenorphine is a potent analgesic agent with several unique and favourable features such as its sublingual formulation. The aim of this study is to compare the effectiveness of sublingual versus intramuscular and intravenous buprenorphine in acute pain.MethodsFive major databases were systema...