Eosinophil Purification from Peripheral Blood of Rhesus Monkeys

• Published in: Methods in molecular biology (Clifton, N.J.) Vol. 2241; p. 27
• Main Author: Legrand, Fanny
• Format: Journal Article
• Language: English
• Published: United States 2021
• Subjects: Animals; Blood - metabolism; Blood Cells - cytology; Cell Separation - methods; Centrifugation, Density Gradient - methods; Eosinophils - cytology; Eosinophils - metabolism; Eosinophils - physiology; Flow Cytometry - methods; Immunomagnetic Separation - methods; Leukocyte Count - methods; Macaca mulatta - immunology; Receptors, IgG - immunology; CD64; Granulocytes; Macaques; Nonhuman primates; Cell separation; Cell isolation; Eosinophils; Rhesus monkeys

Eosinophils are granulocytes involved mainly in allergic inflammation and parasitic responses and constitute 1-5% of the circulating leukocytes in human healthy subjects. New immunotherapies targeting eosinophils have been developed and evaluated recently, and the availability of animal models that...