Synthesis, structural and chemosensitivity studies of arene d6 metal complexes having N‐phenyl‐N´‐(pyridyl/pyrimidyl)thiourea derivatives

• Published in: Applied organometallic chemistry Vol. 32; no. 6
• Main Authors: Adhikari, Sanjay, Hussain, Omar, Phillips, Roger M., Kaminsky, Werner, Kollipara, Mohan Rao
• Format: Journal Article
• Language: English
• Published: Chichester Wiley Subscription Services, Inc 01.06.2018
• Subjects: Cancer; Cations; Chelation; Chemistry; chemosensitivity; Coordination compounds; Crystallography; Cytotoxicity; Epithelium; Iridium; Iridium compounds; Ligands; Metal compounds; Metals; Rhodium; Ruthenium; thiourea; Thiourea derivatives; Thioureas; Toxicity

The d6 metal complexes of thiourea derivatives were synthesized to investigate its cytotoxicity. Treatment of various N‐phenyl‐N´ pyridyl/pyrimidyl thiourea ligands with half‐sandwich d6 metal precursors yielded a series of cationic complexes. Reactions of ligand (L1‐L3) with [(p‐cymene)RuCl2]2 and...