THUMPD3-ASI Is Correlated With Non-Small Cell Lung Cancer And Regulates Self-Renewal Through miR-543 And ONECUT2

• Published in: OncoTargets and therapy p. 9849
• Main Authors: Hu, Jia, Chen, Youfang, Li, Xiaodong, Miao, Huikai, Li, Rongzhen, Chen, Dongni, Wen, Zhesheng
• Format: Journal Article
• Language: English
• Published: Dove Medical Press Limited 01.11.2019
• Subjects: Analysis; Death; Genes; Health aspects; Lung cancer; MicroRNA; Molecular biology; Non-small cell lung cancer; RNA; Small cell lung cancer; Tumors; China

Background: Of all malignancies, lung cancer is the leading cause of death, and non-small cell lung cancer (NSCLC) accounts for 80-85% of all lung cancers. In this study, the long non-coding RNA (lncRNA) THUMPD3-AS1 was observed to be highly expressed in NSCLC and correlated with TNM stages and rela...