The NPC1L1 Polymorphism 1679CG Is Associated with Gallstone Disease in Chinese Patients

• Published in: PloS one Vol. 11; no. 1
• Main Authors: Wu, Jian, Cui, Wei, Cai, Qu, Fei, Jian, Zhang, Sheng-Dao, Han, Tian-Quan, Hu, Hai, Jiang, Zhao-Yan
• Format: Journal Article
• Language: English
• Published: Public Library of Science 22.01.2016
• Subjects: Care and treatment; Development and progression; Gallstones; Patient outcomes; Single nucleotide polymorphisms; United States

Niemann Pick Type C1 Like 1 (NPC1L1) protein plays a key role in intestinal and hepatic cholesterol metabolism in humans. Genetic variation in NPC1L1 has been widely studied in recent years. We analyzed NPC1L1 single nucleotide polymorphisms in Chinese gallstone disease patients to investigate their...