Safety of the Malaria Vaccine Candidate, RTS,S/AS01.sub.E in 5 to 17 Month Old Kenyan and Tanzanian Children

• Published in: PloS one Vol. 5; no. 11; p. e14090
• Main Authors: Lusingu, John, Olotu, Ally, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Olivier, Aurélie, Benns, Sarah, Olomi, Raimos, Msham, Salum, Lang, Trudie, Gould, Jayne, Hallez, Karin, Guerra, Yolanda, Njuguna, Patricia, Awuondo, Ken O, Malabeja, Anangisye, Abdul, Omar, Gesase, Samwel, Dekker, Denise, Malle, Lincoln, Ismael, Sadiki, Mturi, Neema, Drakeley, Chris J, Savarese, Barbara, Villafana, Tonya, Ballou, W. Ripley, Cohen, Joe, Riley, Eleanor M, Lemnge, Martha M, Marsh, Kevin, Bejon, Philip, von Seidlein, Lorenz
• Format: Journal Article
• Language: English
• Published: Public Library of Science 29.11.2010
• Subjects: Gastroenteritis; Malaria; Malaria vaccines; Medical research; Vaccination; Vaccines

The malaria vaccine candidate, RTS,S/AS01.sub.E, showed promising protective efficacy in a trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we report on the vaccine's safety and tolerability. The experimental design was a Phase 2b, two-centre, double-blind (observer- and partici...