m[sup.6]A Methyltransferase KIAA1429 Regulates the Cisplatin Sensitivity of Gastric Cancer Cells via Stabilizing FOXM1 mRNA

• Published in: Cancers Vol. 14; no. 20
• Main Authors: Zhu, Zhongcheng, Zhou, Yuan, Chen, Yongheng, Zhou, Zhongyi, Liu, Wenxue, Zheng, Linyi, Pei, Qian, Tan, Fengbo, Pei, Haiping, Li, Yuqiang
• Format: Journal Article
• Language: English
• Published: MDPI AG 01.10.2022
• Subjects: Cisplatin; Dosage and administration; Drug therapy; Genetic aspects; Health aspects; Messenger RNA; Methyltransferases; Patient outcomes; Stomach cancer; China

N6-methyladenosine (m[sup.6] A) is involved in the development of drug resistance in various cancer types. The role of N6-methyladenosine (m[sup.6] A) methyltransferase, KIAA1429, in the resistance of gastric cancer to cisplatin is largely unknown. In this study, the KIAA1429 expression level as wel...