Hydroxybutyrate, One of the Three Main Ketone Bodies, Ameliorates Acute Pancreatitis in Rats by Suppressing the NLRP3 Inflammasome Pathway

• Published in: The Turkish journal of gastroenterology Vol. 32; no. 8; p. 702
• Main Authors: Sahin, Erhan, N.Aykanat, Ezgi Bektur, Kacar, Sedat, Bagci, Ridvan, Sahinturk, Varol
• Format: Journal Article
• Language: English
• Published: AVES 01.08.2021
• Subjects: Beta-hydroxybutyrate; Development and progression; Drug therapy; Health aspects; Pancreatitis; Physiological aspects; Turkey

Background: Acute pancreatitis (AP) is a widespread disease resulting from the inflammation of acinar cells in the pancreas. [beta]-hydroxybutyrate (BHB) is a water-soluble main ketone body synthesized in the human liver. The purpose of this study was to examine the possible therapeutic effects of B...