Nuclear protein p8 is associated with glucose-induced pancreatic β-cell growth

• Published in: Diabetes (New York, N.Y.) Vol. 53; no. 2; p. S82
• Main Authors: Path, Gunter, Opel, Anne, Knoll, Anita, Seufert, Jochen
• Format: Journal Article
• Language: English
• Published: American Diabetes Association 01.02.2004
• Subjects: Care and treatment; Dextrose; Diabetes; Glucose; Health aspects; Pancreatic beta cells; Protein kinases; Germany

On its own, glucose is a major factor for proliferation of pancreatic β-cells and is also an essential prerequisite for IGF-I and growth hormone-induced growth of these cells, p8 was originally identified as an emergency gene product upregulated in pancreatic acinar cells in response to acute pancre...