The polymorphism analysis and therapy vaccine target epitopes screening of HPV-35 E6 E7 among the threaten [alpha]-9 HPV in Sichuan area

• Published in: Virology journal Vol. 21; no. 1
• Main Authors: He, Jiaoyu, Li, Tianjun, Cheng, Chunlan, Li, Ning, Gao, Peng, Lei, Dan, Liang, Rong, Ding, Xianping
• Format: Journal Article
• Language: English
• Published: BioMed Central Ltd 09.09.2024
• Subjects: Antigenic determinants; Control; Genetic aspects; Papillomaviruses; Physiological aspects; Testing; Vaccines; Viral proteins; Virus research; China

High-risk human papilloma virus (HR-HPV) persistent infection is closely associated with the development of cervical cancer and squamous intraepithelial lesion (SIL).The [alpha]-9 HPVs, which is predominantly composed of HR-HPV types, account for 75% of HR-HPV infection in Sichuan. The oncoproteins...