Cardiac Fas Receptor-dependent Apoptotic Pathway in Obese Zucker Rats

• Published in: Obesity research Vol. 15; no. 10; pp. 2407 - 2415
• Main Authors: Lee, Shin-Da, Tzang, Bor-Show, Kuo, Wei-Wen, Lin, Yueh-Min, Yang, Ai-Lan, Chen, Szu-Hua, Tsai, Fuu-Jen, Wu, Fong-Li, Lu, Min-Chi, Huang, Chih-Yang
• Format: Journal Article
• Language: English
• Published: The North American Association for the Study of Obesity 01.10.2007
• Subjects: animal models; apoptosis; biochemical pathways; body measurements; cardiac molecular mechanism; Fas death receptors; Fas-associated Death Domain; fibrosis; heart; heart diseases; heart ventricle; histology; myocardium; obesity; rats; receptors; tibia; tissue weight

OBJECTIVE: Very limited information regarding the cardiac molecular mechanism in obesity is available. The purpose of this study was to evaluate the cardiac Fas receptor-dependent (type I) apoptotic pathway in obese Zucker rats. RESEARCH METHODS AND PROCEDURES: Sixteen obese Zucker rats were studied...