Neurokine receptors and lipid rafts

• Published in: Journal of neurochemistry Vol. 101; no. 3; pp. 782 - 793
• Main Authors: Port, Martha D, Gibson, Robin M, Nathanson, Neil M
• Format: Journal Article
• Language: English
• Published: Oxford, UK : Blackwell Publishing Ltd 01.05.2007
• Subjects: ciliary neurotrophic factor; cytokine; glycoprotein 130; leukemia inhibitory factor; raft

Leukemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) are cytokines which signal through receptor complexes that include the receptor subunits glycoprotein 130 (gp130) and the LIF receptor (LIFR), but CNTF also requires the non-signal transducing CNTF receptor (CNTFR) for binding....